Structure & Dynamics of Enzymes

Structure & Dynamics of Enzymes


  1. N Ando. "Thinking Outside of the Lattice." ACA RefleXions (2020) Spring Issue, p. 7-10. [web]
  2. SP Meisburger, DA Case, N Ando. "Diffuse X-ray Scattering from Correlated Motions in a Protein Crystal." Nature Communications (2020) 11, Article number: 1271. [web] Pre-print on bioRXiv.
  3. WC Thomas, FP Brooks III, AA Burnim, JP Bacik, J Stubbe, JT Kaelber, JZ Chen, N Ando. "Convergent Allostery in Ribonucleotide Reductase." Nature Communications (2019), 10, Article number: 2653. [web] Pre-print on bioRXiv. [F1000 recommended]
  4. CA Khan, SP Meisburger, N Ando, and PF Fitzpatrick. "The phenylketonuria-associated substitution R68S converts phenylalanine hydroxylase to a constitutively active enzyme but reduces its stability." J Biol Chem (2019), 294: 4359-4367. [web]
  5. A Tinoco, Y Wei, DM Carminati, JP Bacik, EJ Moore, N Ando, Y Zhang, and R Fasan. "Origin of high stereocontrol in olefin cyclopropanation catalyzed by an engineered carbene transferase." ACS Catalysis (2019), 9: 1514–1524 [web]
  6. MJ Parker, AO Maggiolo*, WC Thomas*, A Kim, SP Meisburger, N Ando**, AK Boal**, and J Stubbe**. “An endogenous dAMP ligand in Bacillus subtilis class Ib RNR promotes assembly of a noncanonical dimer for regulation by dATP”. PNAS (2018), 115: E4594-E4603. [web] *equal contributions, **co-corresponding
  7. S Shoemaker and N Ando. “X-rays in the cryo-electron microscopy era: Structural biology’s dynamic future”. Biochemistry (2018), 57: 277–285. [web]. (“Future of Biochemistry” special issue).
  8. KM Davis, KR Schramma, WA Hansen, JP Bacik, SD Khare, MR Seyedsayamdost, and N Ando. “Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition,” PNAS (2017), 114: 10420–10425 (2017). [web]
  9. SP Meisburger*, WC Thomas*, MB Watkins*, and N Ando. “X-ray scattering studies of protein structural dynamics,” Chemical Reviews (2017), 117: 7615-8480. *equal contributions [web] (invited) See also: Prologue by Susannah Shoemaker.
  10. SP Meisburger and N Ando. “Correlated motions from crystallography beyond diffraction,” Acc Chem Res (2017), 50: 580–583. [web] (invited commentary for “Holy Grails in Chemistry” special issue).
  11. JK Rustiguel, ROS Soares, SP Meisburger, KM Davis, KL Malzbender, N Ando, M Dias-Baruffi, and MC Nonato. “Full-length model of the human galectin-4 and insights into dynamics of inter-domain communication.” Scientific Reports, 6: 33633 (2016). [web]
  12. SP Meisburger, AB Taylor, CA Khan, S Zhang, PF Fitzpatrick, and N Ando. “Domain movements upon activation of phenylalanine hydroxylase characterized by crystallography and chromatography-coupled small-angle X-ray scattering.” JACS (2016), 138: 6506–6516. [web]
  13. S Skou, RE Gillilan, N Ando. “Synchrotron-based small-angle X-ray scattering (SAXS) of biomacromolecules in solution.” Nature Protocols (2014), 9: 1727–1739. *corresponding. [web].

Publications (pre Ando Lab)

  1. N Ando*, H Li, EJ Brignole, S Thompson, MI McLaughlin, JE Page, FJ Asturias, J Stubbe, CL Drennan*. “Allosteric inhibition of human ribonucleotide reductase by dATP entails the stabilization of a hexamer.” Biochemistry (2016), 55: 373–381. *co-corresponding. [web].
  2. EC Minnihan, N Ando*, EJ Brignole*, L Olshansky*, J Chittuluru, FJ Asturias, CL Drennan, DG Nocera, J Stubbe. “Generation of a stable, aminotyrosyl radical-induced α2β2 complex of Escherichia coli class Ia ribonucleotide reductase,” PNAS (2013), 110: 3835-3840. [web].
  3. N Ando, Y Kung, M Can, G Bender, SW Ragsdale, CL Drennan. “Transient B12-dependent methyltransferase complexes revealed by small-angle X-ray scattering.” JACS (2012) 134: 17945–17954. [web]
  4. CM Zimanyi, N Ando, EJ Brignole, FJ Asturias, J Stubbe, CL Drennan. “Tangled up in knots: Structures of inactivated forms of E. coli class Ia ribonucelotide reductase.” Structure (2012) 20: 1374–1383. [web].
  5. S Wang, Y Meng, N Ando, MW Tate, S Krasnicki, C Yan, Q Liang, J Lai, H Mao, SM Gruner, RJ Hemley. “Single-crystal CVD diamonds as small-angle X-ray scattering windows for high-pressure research.” Journal of Applied Crystallography (2012) 45: 1–5. [web]
  6. Y Kung, N Ando, T Doukov, L Blasiak, G Bender, SW Ragsdale, CL Drennan. “Visualizing molecular juggling within a B12-dependent methyltransferase complex.” Nature (2012) 484: 265–269. [web].
  7. KD Bewley, MA Firer-Sherwood, J-Y Mock, N Ando, CL Drennan, SJ Elliott. “Mind the Gap: Diversity and reactivity relationships among multiheme cytochromes of the MtrA/DmsE family.” Biochemical Society Transactions (2012), 40: 1268–1273. [web].
  8. EJ Brignole*, N Ando, CM Zimanyi, CL Drennan. “The prototypic class Ia ribonucleotide reductase from Escherichia coli: Still surprising after all these years.” Biochemical Society Transactions (2012) 40: 523–530. *equal contributions [web]
  9. N Ando and B Barstow*. “High hydrostatic pressure effects on proteins: Fluorescence studies.” Encyclopedia of Analytical Chemistry, eds R.A. Meyers, John Wiley: Chichester. DOI: 10.1002/9780470027318.a9246. *co-corresponding, invited [web].
  10. N Ando*, EJ Brignole*, CM Zimanyi, MA Funk, K Yokoyama, FJ Asturias, J Stubbe, CL Drennan. “Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase.” PNAS (2011) 108: 21046–21051. *equal contributions [web].
  11. MA Firer-Sherwood*, N Ando*, SJ Elliott, CL Drennan. “Solution-based structural analysis of the decaheme cytochrome, MtrA, by small angle X-Ray scattering and analytical ultracentrifugation.” J. Phys. Chem. B (2011) 115: 11208–11214. *equal contributions [web]
  12. B Barstow, N Ando, CU Kim, SM Gruner. “Coupling of pressure-induced structural shifts to spectral changes in a Yellow Fluorescent Protein.” Biophysical Journal (2009) 97: 1719-1727. [web]
  13. N Ando, B Barstow, WA Baase, A Field, BW Matthews, Sol M. Gruner. “Structural and thermodynamic characterization of T4 lysozyme mutants and the contribution of internal cavities to pressure denaturation.” Biochemistry (2008) 47: 11097-11109. [web]
  14. B Barstow, N Ando, CU Kim, SM Gruner. “Alteration of Citrine structure by hydrostatic pressure explains accompanying spectral shift.” PNAS (2008) 105: 13362-13366. [web]
  15. N Ando, P Chenevier, M Novak, MW Tate, SM Gruner. “High hydrostatic pressure small-angle X-ray scattering cell for protein solution studies featuring diamond windows and disposable sample cells.” Journal of Applied Crystallography (2008) 41: 167-175. [web]
  16. A Batra, C Cohen; H Kim, KI Winey; N Ando, SM Gruner. “Counterion effect on the rheology and morphology of tailored poly(dimethylsiloxane) ionomers.” Macromolecules (2006) 39: 1630-1638. [web]
  17. K Ito, J Chuang, C Alvarez-Lorenzo, T Watanabe, N Ando, AY Grosberg. “Multiple contact adsorption of target molecules by heteropolymer gels.” Macromolecular Symposia (2004) 207: 1. [web]
  18. K Ito, J Chuang, C Alvarez-Lorenzo, T Watanabe, N Ando, AY Grosberg. “Multiple point adsorption in a heteropolymer gel and the Tanaka approach to imprinting: experiment and theory.” Progress in Polymer Science (2003) 28: 1489-1515. [web]